The Conversion of Pyridine Hydroxamic Acids to Amides by Mouse Liver Mitochondria
نویسندگان
چکیده
منابع مشابه
The conversion of pyridine hydroxamic acids to amides by mouse liver mitochondria.
It has been reported previously that a single injection of nicotinamide or 3-acetylpyridine into mice leads to a marked increase in liver diphosphopyridine nucleotide (l-3). In the course of investigation of other pyridine bases and diphosphopyridine nucleotide analogues, it was found that an injection of nicotinohydroxamic acid also led to increased pyridine nucleotide levels in the mouse live...
متن کاملFacile access to amides and hydroxamic acids directly from nitroarenes.
A new method for synthesis of amides and hydroxamic acids from nitroarenes and aldehydes is described. The MnO2 catalyzed thermal deoxygenation of nitrobenzene resulted in formation of a reactive nitroso intermediate which on reaction with aldehydes provided amides and hydroxamic acids. The thermal neat reaction in the presence of 0.01 mmol KOH predominantly led to formation of hydroxamic acid ...
متن کاملNew complexes of peroxidases with hydroxamic acids, hydrazides, and amides.
Horseradish peroxidase forms spectroscopically distinct, reversible complexes with hydroxamic acids (R-CONHOH), hydrazides (RCO-NHNH2), amides (RCONH2), and oc-hydroxyketones (RCO--CHsOH). Binding of these compounds to the enzyme depends on the polar and steric character of R and the hydrogen bonding capacity of-COX-Y (X-Y = NH-OH, NH-NH,, NH-H, CH,OH). Hydroxamate anions and hydrazide cations ...
متن کاملThe conversion of cholesterol-4-C14 to acids and other products by liver mitochondria.
Since the finding by Bloch, Berg, and Rittenberg that rholesterol could be converted to cholic acid in the dog (l), several groups have established bile acids to be the primary end-product of cholesterol degradation by the liver in the intact rat (2,3), rabbit (4), and human (5). Most of the steps involved in the conversion are still unknown, although the experiments of Zabin and Barker (6) and...
متن کاملConversion of glucose to amino acids by brain and liver of the new-born mouse.
In previous studies, 1 day-old mouse brain incubated with uniformly labeled C14-glucose was shown to incorporate significant amounts of radioactivity into the “protein” fraction (1). All of the non-essential amino acids except proline and all of the essential ones except threonine were radioactive and had roughly comparable specific activities (2). The turnover was of such a magnitude as to ind...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1961
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)64332-7